---
title: "How to Set Up Sega Genesis / Mega Drive Emulation in 2026 — BlastEm and Genesis Plus GX"
canonical_url: https://emudesk.com/issues/sega-genesis-mega-drive-emulator-setup-guide-complete-2026
content_locale: en
source_locale: en
entity_type: issue
index_status: index
published_at: 2026-08-31T18:22:23.000Z
updated_at: 2026-09-01T00:45:02.182Z
freshness_status: fresh
---

# How to Set Up Sega Genesis / Mega Drive Emulation in 2026 — BlastEm and Genesis Plus GX

I want to emulate Sega Genesis and Mega Drive games on PC. I see two main options — BlastEm and Genesis Plus GX. Which should I use, and how do I set either one up? I also want to play Sega CD games — do those need BIOS files, and what ROM format should I use?